Alfred C. H. Yu
Biomedical Ultrasound Laboratory


JOURNAL ARTICLES

  1. Effects of beam steering in pulsed-wave ultrasound velocity estimation
    AH Steinman, ACH Yu, KW Johnston, RSC Cobbold. Ultrasound in Medicine and Biology, vol. 31, no. 8, pp. 1073-1082, 2005.
  2. Transit-time broadening in pulsed Doppler ultrasound: a generalized amplitude modulation model
    ACH Yu, AH Steinman, RSC Cobbold. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 53, no. 3, pp. 530-541, 2006.
  3. Frequency-based signal processing for ultrasound color flow imaging
    ACH Yu, KW Johnston, RSC Cobbold. Canadian Acoustics, vol. 35, no. 2, pp. 11-23, 2007. (Special Issue Paper)
  4. Coded excitation methods for ultrasound harmonic imaging
    R Arshadi, ACH Yu, RSC Cobbold. Canadian Acoustics, vol. 35, no. 2, pp. 35-46, 2007. (Special Issue Paper)
  5. An automated carotid pulse assessment approach using Doppler ultrasound
    ACH Yu*, E Cohen-Solal, BI Raju, S Ayati. IEEE Transactions on Biomedical Engineering, vol. 55, no. 3, pp. 1072-1081, 2008.
  6. Single-ensemble-based eigen-processing methods for color flow imaging -- Part I. The Hankel-SVD filter
    ACH Yu, RSC Cobbold. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 55, no. 3, pp. 559-572, 2008.
  7. Single-ensemble-based eigen-processing methods for color flow imaging -- Part II. The Matrix Pencil estimator
    ACH Yu, RSC Cobbold. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 55, no. 3, pp. 573-586, 2008.
  8. Electrocardiogram amplifier design using basic electronic parts
    ACH Yu*. IEEE Real World Engineering Project, No. 591, 2009.
  9. Eigen-based clutter filter design for ultrasound color flow imaging: a review
    ACH Yu*, L Lovstakken. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 57, no. 5, pp. 1096-1111, 2010.
  10. GPU-based beamformer: fast realization of plane wave compounding and synthetic aperture imaging
    BYS Yiu, IKH Tsang, ACH Yu*. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 58, no. 8, pp. 1698-1705, 2011.
  11. Medical ultrasound imaging: to GPU or not to GPU?
    HKH So, J Chen, BYS Yiu, ACH Yu*. IEEE Micro, vol. 31, no. 5, pp. 54-65, 2011. (Special Issue Paper)
  12. Sonoporation induces apoptosis and cell cycle arrest in human promyelocytic leukemia cells
    W Zhong, WH Sit, JMF Wan, ACH Yu*. Ultrasound in Medicine and Biology, vol. 37, no. 12, pp. 2149-2159, 2011.
  13. Design space exploration of adaptive beamforming acceleration for bedside and portable medical ultrasound imaging
    J Chen, BYS Yiu, B Hamilton, ACH Yu, HKH So. ACM SIGARCH Computer Architecture News, vol. 39, no. 4, pp. 20-25, 2011.
  14. Multi-channel pre-beamformed data acquisition system for research on advanced ultrasound imaging methods
    CCP Cheung, ACH Yu*, N Salimi, BYS Yiu, IKH Tsang, B Kerby, RZ Azar, K Dickie. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 59, no. 2, pp. 243-253, 2012.
  15. Ultrasound-microbubble mediated cavitation of plant cells: effects on morphology and viability
    P Qin, L Xu, W Zhong, ACH Yu*. Ultrasound in Medicine and Biology, vol. 38, no. 6, pp. 1085-1096, 2012.
  16. Subcellular impact of sonoporation on plant cells: issues to be addressed in ultrasound-mediated gene transfer
    P Qin, L Xu, P Cai, Y Hu, ACH Yu*. Ultrasonics Sonochemistry, vol. 20, no. 1, pp. 247-253, 2013.
  17. Ultrasound can modulate neuronal development: impact on neurite growth and cell body morphology
    Y Hu, W Zhong, JMF Wan, ACH Yu*. Ultrasound in Medicine and Biology, vol. 39, no. 5, pp. 915-925, 2013.
  18. High frame rate ultrasound color-encoded speckle imaging of complex flow dynamics
    BYS Yiu, ACH Yu*. Ultrasound in Medicine and Biology, vol. 39, no. 6, pp. 1015-1025, 2013.
  19. Sonoporation as a cellular stress: induction of morphological repression and developmental delays
    X Chen, JMF Wan, ACH Yu*. Ultrasound in Medicine and Biology, vol. 39, no. 6, pp. 1075-1086, 2013.
  20. Design of anthropomorphic flow phantoms based on rapid prototyping of compliant vessel geometries
    SSM Lai, BYS Yiu, AKK Poon, ACH Yu*. Ultrasound in Medicine and Biology, 2013, in-press.

CONFERENCE PROCEEDINGS AND PRESENTATIONS

  1. Transit time broadening: a pulsed Doppler ultrasound perspective
    ACH Yu, AH Steinman, EYL Lui, RSC Cobbold. Proceedings of IEEE Ultrasonics Symposium, pp. 2113-2116, 2004.
  2. A new eigen-based flow estimator using the Matrix Pencil approach
    ACH Yu, LYL Mo, RK Warriner, RSC Cobbold. Proceedings of IEEE Ultrasonics Symposium, pp. 1335-1338, 2005.
  3. A new eigen-based clutter filter using the Hankel-SVD approach
    ACH Yu, RSC Cobbold. Proceedings of IEEE Ultrasonics Symposium, pp. 1079-1082, 2006.
  4. A Matrix Pencil estimator with adaptive rank selection: application to in vivo flow studies
    ACH Yu, RSC Cobbold. Proceedings of IEEE Ultrasonics Symposium, pp. 2015-2018, 2006.
  5. Eigen-based clutter filters for color flow imaging: single-ensemble vs. multi-ensemble approaches
    ACH Yu*, L Lovstakken. Proceedings of IEEE Ultrasonics Symposium, pp. 1101-1104, 2007.
  6. In-vivo investigation of filter order influence in eigen-based clutter filtering for color flow imaging
    L Lovstakken, ACH Yu, H Torp. Proceedings of IEEE Ultrasonics Symposium, pp. 2429-2432, 2007.
  7. A modified synthetic aperture imaging approach with axial motion compensation
    BYS Yiu, IKH Tsang, ACH Yu*. Proceedings of IEEE Ultrasonics Symposium, pp. 1254-1257, 2008.
  8. Ultrasound wave propagation in time-varying phononic crystals
    DW Wright, ACH Yu, RSC Cobbold. Proceedings of IEEE Ultrasonics Symposium, pp. 1491-1494, 2008.
  9. Towards integrative learning in biomedical engineering: a project course on electrocardiogram monitor design
    ACH Yu*, BYS Yiu, IKH Tsang, PYS Cheung. Proceedings of ASEE-IEEE Frontiers in Education Conference, No. T4J-1265, 2009.
  10. Ultrasound-enhanced osteogenesis of human mesenchymal stem cells encapsulated in collagen meshwork
    HCT Wong, MY Wong, BP Chan, ACH Yu*. Proceedings of IEEE Ultrasonics Symposium, pp. 361-364, 2009.
  11. Design of a multi-channel pre-beamform data acquisition system for an ultrasound research scanner
    IKH Tsang, BYS Yiu, DKH Cheung, HCT Chiu, CCP Cheung, ACH Yu*. Proceedings of IEEE Ultrasonics Symposium, pp. 1840-1843, 2009.
  12. A least-squares vector flow estimator for synthetic aperture imaging
    IKH Tsang, BYS Yiu, ACH Yu*. Proceedings of IEEE Ultrasonics Symposium, pp. 1387-1390, 2009.
  13. Sonoporation-induced apoptosis and cell cycle arrest: initial findings
    W Zhong, WH Sit, JMF Wan, ACH Yu*. Proceedings of International Symposium on Therapeutic Ultrasound, pp. 361-365, 2010.
  14. Assessing students' integrative learning in biomedical engineering from the perspectives of structure, behavior, and function
    YY Chan, ACH Yu, CKK Chan. Proceedings of ASEE-IEEE Frontiers in Education Conference, No. S1G-1418, 2010.
  15. Real world engineering projects: discovery-based curriculum modules for first-year students
    J Carletta, P Bhatti, T Hartlet, Y Liu, A Mitofsky, JA Smith, L Wyard-Scott, ACH Yu. Proceedings of ASEE-IEEE Frontiers in Education Conference, No. T2A-1607, 2010.
  16. Adaptive clutter filter design for micro-ultrasound color flow imaging of small blood vessels
    DKH Cheung, HCT Chiu, L Zhang, C Hu, KK Shung, ACH Yu*. Proceedings of IEEE Ultrasonics Symposium, pp. 1206-1209, 2010.
  17. Cytoplasmic signaling involved in sonoporation-induced apoptosis and mitosis repression of promyelocytic leukemia cells
    W Zhong, WH Sit, JMF Wan, ACH Yu*. Proceedings of IEEE Ultrasonics Symposium pp. 1771-1774, 2010.
  18. Design of a programmable micro-ultrasound research platform
    HCT Chiu, L Zhang, DKH Cheung, C Hu, KK Shung, ACH Yu*. Proceedings of IEEE Ultrasonics Symposium, pp. 1980-1983, 2010.
  19. Real-time GPU-based software beamformer designed for advanced imaging methods research
    BYS Yiu, IKH Tsang, ACH Yu*. Proceedings of IEEE Ultrasonics Symposium, pp. 1920-1923, 2010.
  20. Low-intensity pulsed ultrasound enhances differentiation of osteolineage-committed human mesenchymal stem cells
    LCH Poon, MY Wong, BP Chan, ACH Yu*. International Symposium on Therapeutic Ultrasound, 2011. (Abstract)
    (3rd Place, Student Paper Competition)
  21. Suppression of HeLa cancer cell proliferation in-vitro through sonoporation
    X Chen, WH Sit, JMF Wan, W Zhong, ACH Yu*. International Symposium on Therapeutic Ultrasound, 2011. (Abstract)
  22. Towards developing a plant-based experimental model for sonoporation-mediated gene therapy: bioeffects analysis
    P Qin, L Xu, W Zhong, ACH Yu*. International Symposium on Therapeutic Ultrasound, 2011. (Abstract)
  23. High frame rate vector flow imaging of stenotic carotid bifurcation: computational modeling and analysis
    DLS Chan, BYS Yiu, ACH Yu*. Proceedings of IEEE Ultrasonics Symposium, pp. 409-412, 2011.
  24. Real-time GPU-based adaptive beamformer for high quality ultrasound imaging
    J Chen, BYS Yiu, HKH So, ACH Yu*. Proceedings of IEEE Ultrasonics Symposium, pp. 474-477, 2011.
  25. Developing a new model for sonoporation treatment using plants: cellular mechanism analysis
    P Qin, L Xu, W Zhong, ACH Yu*. Proceedings of IEEE Ultrasonics Symposium, pp. 616-619, 2011.
  26. Heat shock protein expression in sonoporated myeloid leukemia cells
    W Zhong, P Jiang, H Wang, JMF Wan, ACH Yu*. IEEE Ultrasonics Symposium, 2011. (Abstract)
  27. Biosafety investigation of acoustic cavitation on cells in the immune system: analysis on human T-lymphocytes
    W Zhong, WH Sit, J Zhang, JMF Wan, ACH Yu*. IEEE Ultrasonics Symposium, 2011. (Abstract)
  28. Influence of biomechanical factors in thoracic aortic dissection: a computational fluid dynamics study
    YS Tang, SK Lai, SWK Cheng, KW Chan, ACH Yu, KW Chow. International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, No. 18, 2012.
  29. High frame rate velocity-coded speckle imaging platform for coherent blood flow visualization
    ACH Yu*, BYS Yiu. ASA Acoustics Conference, 2012. (Abstract)
  30. Characteristics of sonoporated cells after resealing: reduced cell size and increased granularity
    X Chen, WH Sit, JMF Wan, ACH Yu*. International Symposium on Therapeutic Ultrasound, 2012. (Abstract)
  31. Ultrasound as a regulator of neuronal development: morphological impact on neuro-2a cells
    Y Hu, W Zhong, WH Sit, JMF Wan, ACH Yu*. International Symposium on Therapeutic Ultrasound, 2012. (Abstract)
  32. Ultrasound-induced neuronal membrane depolarization in-vitro
    Y Hu, WH Sit, JMF Wan, ACH Yu*. IEEE Ultrasonics Symposium, 2012. (Abstract)
  33. Color-encoded speckle imaging (CESI): a novel high-frame-rate approach to coherent visualization of complex flow dynamics
    ACH Yu*, BYS Yiu. Proceedings of Symposium on Ultrasonic Electronics, pp. 141-142, 2012.
    (Young Scientist Award)
  34. Design considerations of real-time adaptive beamformer for medical ultrasound research using FPGA and GPU
    J Chen, ACH Yu, HKH So. Proceedings of International Conference on Field Programmable Technology, pp. 198-205, 2012.

THESES

  1. Investigation of transit time broadening in pulsed-wave Doppler ultrasound
    ACH Yu. MASc Thesis, University of Toronto, Toronto, ON, Canada, 2004.
  2. Eigen-based signal processing methods for ultrasound color flow imaging
    ACH Yu. PhD Thesis, University of Toronto, Toronto, ON, Canada, 2007.