Quantitative susceptibility mapping (QSM): biometal imaging and its applications
Date:
15 Nov, 2017 (Wed)
Time:
11:00 am
Location:
Room 601J

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Speaker

Prof. Yi Wang, PhD
Department of Biomedical Engineering & Radiology,
Cornell University, New York, USA

Abstract

Quantitative susceptibility mapping (QSM) is based on the Bayesian solution to the magnetic field to susceptibility source inverse problem. QSM has become sufficiently accurate and robust for routine applications. QSM is advancing MRI of tissue magnetic susceptibility from simple qualitative detection of hypointense blooming artifacts to precise measurement of biodistributions. Tissue susceptibility contains rich functional and structural information pertinent to molecular electron cloud properties. The dominant susceptibility sources in tissue are biometals, which are vital participants in cellular functions and pathologies. QSM can be useful for diseases that involve neurodegeneration, inflammation, hemorrhage, abnormal oxygen consumption, substantial alterations in highly paramagnetic cellular iron, bone mineralization, or pathologic calcification; and for all disorders in which MRI diagnosis or surveillance requires contrast agent injection. Clinicians should consider integrating QSM into their routine imaging practices by including gradient echo sequences in all relevant MRI protocols.

 

Biography of the speaker:

Prof. Yi Wang holds the Faculty Distinguished Professorship at the Department of Radiology, and is a tenured Professor of Physics in Radiology, Professor of Biomedical Engineering, and the Principal Investigator of the 3T MRI facility at Cornell University. He studied theoretical physics and switched to applying physics in medicine. Prof. Wang has invented multiple MRI technologies that are very important to the clinical and scientific communities: i) the cardiac navigator method to compensate for motion artifacts that has been adapted by most major academic centers as a basic approach in cardiac MRI; ii) the time-resolved acquisition method to solve the critical problem of timing acquisition to contrast bolus arrival in clinical contrast enhanced MRA and the multiple-station stepping-table platform to offer high throughput imaging of various body parts; iii) the quantitative susceptibility mapping (QSM) method that has broken ground for a new field in MRI for studying tissue magnetism.


Organizer

Prof. E.X. Wu
Jointly organized by “EEE” & ”SRT Biomedical Engineering and Nanotechnology”

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