RPG Seminar – Photoacoustic microscopy (PAM) at 1.7µm
Date:
19 Apr, 2021 (Mon)
Time:
4:00 pm
Webinar Link:
https://hku.zoom.us/j/92905063389?pwd=VDZnMlZFZmlkcWJuUWdhRTV2MjJWdz09

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Speaker

Mr. Jiawei Shi
Department of Electrical and Electronic Engineering
The University of Hong Kong

Abstract

Vibrational photoacoustic imaging at the third near-infrared window has been demonstrated as a promising tool for label-free imaging of lipid-rich tissues, including arterial plaque in atherosclerosis and the myelin sheath of nerves. By irradiating the C-H bond with an energetic short laser pulse at its first overtone band (∼1725 nm), acoustic signals proportional to the lipid content may be generated. Photoacoustic imaging of lipid at the 1.7 µm has three main advantages: First, it is label-free, facilitating its clinical translation; secondly, it enables achieving higher penetration depths with optical focusing owing to the low tissue scattering at longer wavelengths; thirdly, it enables the use of higher laser powers owing to the lower photo damage associated with long wavelengths.

In this talk, I will present three cost-effective and efficient thulium-doped fiber laser (TDFL) at 1.7 mm for the photoacoustic microscopy of lipid-rich tissue, and ameliorate its performance in terms of image contrast, laser power requirement, and system stability by leveraging two nonlinear excitation methods: Grüeneisen-relaxation illumination and double illumination.



Biography of the speaker:
Jiawei Shi received the B.S. degree in electrical engineering from City University of Hong Kong, Hong Kong in 2017. He is currently working toward Ph.D. degree at The University of Hong Kong. His research interest is high-power fiber laser at longer infrared region and contrast-enhanced photoacoustic microscopy.


Organizer

Prof. Kenneth K. Y. Wong

Most seminars are open to the general public, free of charge, unless otherwise stated. Registration is not required. Arrangement for car parking facilities on campus please contact us for details.

For enquiries, please contact:
Department of Electrical and Electronic Engineering,
Room 601, Chow Yei Ching Building,
Pokfulam Road, Hong Kong
Tel: (852) 3917 7093
Email: seminar@eee.hku.hk