19 Apr, 2021 (Mon)Time:
4:00 pmWebinar Link:
SpeakerMr. Jiawei Shi
Department of Electrical and Electronic Engineering
The University of Hong Kong
Vibrational photoacoustic imaging at the third near-infrared window has been demonstrated as a promising tool for label-free imaging of lipid-rich tissues, including arterial plaque in atherosclerosis and the myelin sheath of nerves. By irradiating the C-H bond with an energetic short laser pulse at its first overtone band (∼1725 nm), acoustic signals proportional to the lipid content may be generated. Photoacoustic imaging of lipid at the 1.7 µm has three main advantages: First, it is label-free, facilitating its clinical translation; secondly, it enables achieving higher penetration depths with optical focusing owing to the low tissue scattering at longer wavelengths; thirdly, it enables the use of higher laser powers owing to the lower photo damage associated with long wavelengths.
In this talk, I will present three cost-effective and efficient thulium-doped fiber laser (TDFL) at 1.7 mm for the photoacoustic microscopy of lipid-rich tissue, and ameliorate its performance in terms of image contrast, laser power requirement, and system stability by leveraging two nonlinear excitation methods: Grüeneisen-relaxation illumination and double illumination.
Biography of the speaker:
Jiawei Shi received the B.S. degree in electrical engineering from City University of Hong Kong, Hong Kong in 2017. He is currently working toward Ph.D. degree at The University of Hong Kong. His research interest is high-power fiber laser at longer infrared region and contrast-enhanced photoacoustic microscopy.
OrganizerProf. Kenneth K. Y. Wong
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